Urethral collagen injections are a minimally invasive procedure to restore urinary continence. As opposed to medical therapies, collagen is injected into the urethral sphincter to help give it more tone. The procedure is performed through the use of cameras without surgical incisions. Not every patient is an appropriate candidate for this procedure and careful selection is required.


Why it’s done

Your veterinarian may recommend urethral collagen injections if your pet has:

  • A history of urinary incontinence particularly when asleep or lying down

How to prepare for your pet’s procedure

Before your pet’s procedure, you will meet with one of our specialists to talk about the procedure and what to expect.

When you meet with our team, please bring a list of all medications that your pet is currently taking, including over the counter medications, vitamins, and herbal supplements. Before your pet’s procedure, you may be asked to discontinue giving certain medications that can increase the risk of bleeding.

This is a good time to ask questions about the procedure and make sure you understand the risks and benefits.

Preoperative diagnostics and tests

Before your pet’s urethral collagen procedure the following may be indicated:

  • Abdominal ultrasound
  • Comprehensive blood tests
  • Urinalysis and urine culture

General Instructions for the Day of Surgery

  • Give your pet nothing by mouth after midnight the night before. This means that all food and water should be withheld.
  • Please arrive for pet’s admission promptly at your scheduled arrival time.
  • You will be asked to sign both a Surgical Consent Form as well as an Estimate, indicating your understanding of the procedure, risks, and associated costs.

What happens during a urethral collagen procedure?

Your pet will be given a general anesthetic. A lighted instrument with a camera on the end, called a cystoscope, is used to help locate the urethral sphincter near the neck of the bladder. A special needle is advanced through the camera and the collagen is injected into several locations in the urethral sphincter restoring continence.


Complications associated with urethral collagen injections can include the following:

  • Bloody urine
  • Discomfort or straining while urinating
  • Infection
  • Bladder or ureteral rupture (exceedingly rare complication)

After the procedure

  • Following the procedure, you will be given a phone call with an update on your pet’s recovery. A scheduled discharge will be coordinated at that time.
  • Please remove the bandage from your pet’s intravenous catheter site 10 to 15 minutes after arriving home.
  • Some abdominal tenderness is common for 3-5 days following urethral collagen injections.
  • It is important to restrict your pet’s activity for the next 3-5 days while your pet is healing. Walks should be short and your pet should always be on a leash. Please do not let your pet rough house with other animals during this time.
  • Many patients will not eat the night following anesthesia. If your pet has not eaten after 24 hours of returning home, please call Salt River.
  • Some patients will vomit or have diarrhea following anesthesia. If the vomiting or diarrhea persists more than 24 hours, please call Salt River. In contrast, some patients may be constipated or may not have a bowel movement for up to 72 hours following anesthesia. If your pet is straining to defecate after 72 hours, please call Salt River.
  • Suture removal is not necessary since no incisions are made.
  • Scooting and more frequent urinations are common for 1-3 days following the procedure, but generally improve with each passing day. If the issues continue beyond 3 days, please call Salt River.
  • An e-collar may be necessary if your pet is licking at its penis or vulva excessively.


Samples may be submitted to a number of specialized laboratories for evaluation including the following tests:

  • Bacterial cultures

The final culture results can take up to 7-10 days. Once the final results have returned and a treatment plan has been devised, our specialists will call you to discuss the findings and recommendations.

Follow up

A recheck appointment is required 7-10 days following the procedure.